BDBM126621 US10562854, No. B5::US8778412, B5::US9278930, B5

SMILES OCC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O

InChI Key InChIKey=MSVZUQFXRBMZGG-QGZVFWFLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 126621   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM126621(US10562854, No. B5 | US8778412, B5 | US9278930, B5)
Affinity DataIC50:  5.30E+4nMAssay Description:HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM126621(US10562854, No. B5 | US8778412, B5 | US9278930, B5)
Affinity DataIC50:  5.30E+4nMAssay Description:VEGF: HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following ove...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM126621(US10562854, No. B5 | US8778412, B5 | US9278930, B5)
Affinity DataIC50:  5.30E+4nMAssay Description:HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...More data for this Ligand-Target Pair
In DepthDetails US Patent